ABSTRACT:

Orthopaedic pathologies such as osteoarthritis (OA) affect lower extremity joint health and function. Standard clinical diagnosis of OA, using x-rays, may not provide early indications of joint degeneration consisting of the loss of articular cartilage. The Musculoskeletal Quantitative Imaging Research (MQIR) group at the University of California-San Francisco uses quantitative magnetic resonance imaging (QMRI) techniques and in-vivo biomechanics to better understand the effects of OA on lower extremity joint function and health. More specifically, the MQIR group has pioneered QMRI techniques that provide early signs of altered cartilage composition and the lower extremity biomechanics that are associated with these potential early signs of cartilage degeneration. This combined approach of QMRI and biomechanics may aid clinicians and researchers in development of interventions that help to prevent the onset or progression of joint degeneration.

A presentation by Michael Samaan, Ph.D.