Processing 3D Printed Molds for Droplet Generating Microfluidic Devices

Authors: Syed Rahim

Advisors: Dr. Liat Rosenfeld, Dr. Melinda Simon

Microfluidic devices have excellent potential to be prognostic or diagnostic medical systems due to their small form factor, high scalability, rapid testing processes, and low cost of production.  Traditional methods for fabrication of these devices require training in wet lab procedures and operation of machinery to create microfluidic devices.  Barrier-to-entry for fabrication of microfluidic devices can be lowered substantially by using an additively manufactured mold through which microfluidic devices can be cast.  This project considers the return on investment of a reusable 3D printed mold versus photolithography and computer numerical control machining of plastic sheets.  This project proves the viability of a reusable 3D printed mold for droplet generation through a flow focusing model by generating micron-sized droplets for PCR applications.