Abstract: Osteolysis Prevention for Titanium Hip Implants
Aseptic loosening is a common occurrence with hip implants due to a lack of osseointegration which often leads to necessary revision surgery . In an effort to prevent the need for revision surgery, a bioactive polymer coating on the implant may be able to promote osseointegration enough to prevent osteolysis from causing aseptic loosening .
As of 2020, the United States has about 40,000 hip arthroplasties that need to be repaired annually due to aseptic loosening; and the number is expected to increase . The lack of osseointegration leads to the hip implant loosening which occurs due to wear debris that can be formed between articulating surfaces, non-articulating surfaces, or between modular interfaces where the implant comes into contact with bone resulting in the production of wear particles .
We have built a feasible mechanical apparatus that will aid in determining the amount of abrasion a titanium implant may inflict on a patient’s femoral cavity wall. The apparatus has been built, but data will not be collected until April 2021. In addition to analyzing the bone sample(s) before and after testing, we will be researching and comparing bioactive polymers that may promote osseointegration. Coating the hip implant in a bioactive polymer may aid in preventing osteolysis from occurring. Results and conclusions will not be completed until May 2021.