Jonas Otoo has a bachelor’s degree in Biochemistry, Cell and Molecular Biology from the University of Ghana, in Ghana. His master’s degree is in Business and Science with a concentration in Biotech Management from Keck Graduate Institute, United States of America. He is currently a second-year doctoral student in Applied Life Sciences at the Keck Graduate Institute. He is interested in translational research in the areas of human metabolic and infectious diseases. His current research area is in infectious diseases. Jonas is working on developing a multiplex Urinary Tract Infection (UTI) diagnostic test using isothermal nucleic acid amplification methods and microfluidic techniques.
Abstract: REASSURED Multiplex Diagnostics for Limited-Resource settings
Diagnosis of infectious diseases is ineffective when the diagnostic test does not meet one or more of the necessary standards of affordability, accessibility, and accuracy. The World Health Organization further clarifies these standards with a set of criteria that has the acronym ASSURED. The advancement of the digital age has led to a revision of the ASSURED criteria to REASSURED: Real-time connectivity, Ease of specimen collection, Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free or simple, and Deliverable to end-users. Many diagnostic tests have been developed that aim to satisfy the REASSURED criteria, however most of them only detect a single target. With the progression of syndromic infections, coinfections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever. This talk summarizes current diagnostic technologies for multiplexed detection and forecasts which methods have promise for detecting multiple targets and meeting all REASSURED criteria.